Vulnerability in EPiServer.Forms
Does EPiServer 6 support .NET 4.5?
It does. To make life easier - search for "EPiServerCMS6ToNetFour" package in EPiServer nuget feed.
If you are migrating site created with Deployment Center - you may need to clean up additional stuff (like various dll redirects, handlers or modules) from web.config file as well.
Alright, thanks Valdis.