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Looks like its trying to create a content type that already exist?
Added any new media types lately? Got guids on them all? If you changed guid on an existing type it would probably generate a similar error to that?...
As of recently I get a server error when I try to create a new folder in the media manager.
"Unable to load /EPiServer/cms/Stores/contentdata/ status: 500",
I already had a look at this topic without any luck http://world.episerver.com/Modules/Forum/Pages/Thread.aspx?id=85177.
This is the callstack: